The PureFlo® Biological Reduction Grade filter capsule in its all-polypropylene construction provides excellent chemical compatibility and superior flow per surface area as compared to other membrane capsules. PureFlo® Biological grade capsules have been designed for bioreduction in pharmaceutical applications. Its hydrophilic PES membrane does not require pre-wetting agents, thereby eliminating a potential source of contamination. The PES membrane is low protein-binding.
The capsules were designed for simple and efficient filtration of small volumes used in low-flow application, laboratory, and pilot runs. No adhesives, binders, or surfactants are used in the manufacturing process of these capsules. They are rinsed with pyrogen-free water to reduce extractables and downtime. All filter capsules are 100% integrity tested to ensure filter performance each and every time out of the package. PureFlo® PES filter capsules are well-suited for pharmaceutical applications where superior flow and bacterial retention is required.
Regulatory Compliance Manufactured from materials that conform to the requirements of 21CFR Part 177 of the U.S. Code of Federal Regulations and the USP Class VI Biological Test for Plastics. ISO 9001, ISO 14001 and ISO 13485 certified.
Water Bubble Point Specification 0.1um: 23psi,0.16 MPA (IPA) 0.2um: 47psi,0.32 MPa 0.45um: 33psi,0.23 MPa Autoclavable and Sanitizable Capsules can be autoclaved up to six times at 126 C for 60 minutes or chemically sanitized in situ using common sanitizing agents such as hot water at 90°C for a limited time (dependent on time and temperature).
Bacterial Endotoxin Effluent is non-pyrogenic per USP Bacterial Endotoxin (0.25 EU/ml), determined using Limulus Amebocyte Lysate (LAL) Test.
Materials of Construction Membrane: Hydrophilic Polyethersulfone Membrane Supports: Polypropylene or PET Cage, Core, End Caps: Polypropylene or Polyethylene option Fitting Connections NPT, Sanitary Flange, Hose Barb Vent/Drain : Luer Lock with Cap
Dimensions (nominal) Length: 1.5 in (100 mm) Length: 2.5 in (125 mm) Length: 5.0 in (220 mm) Length: 10 in (340mm) Diameter: 2.75 in (70 mm)
Effective Filtration Area 1.5 in - 0.77 ft2 (720 cm2) 2.5 in - 1.48 ft2 (1380 cm2) 5.0 in - 2.8 ft2 (2600 cm2) 10 in - 5.6 ft2 (5200 cm2)
Operating Conditions Maximum Forward Differential Pressure: 73 psid (5.0 bar) at 20°C 36 psid (2.5 bar) at 50°C 17 psid (1.2 bar) at 80°C Maximum Reverse Differential Pressure: 44 psid (3.0 bar) at 20°C Maximum Operating Temperature: 80° C
PureFlo® PES Filter Capsule (Biological Grade) Ordering Guide
